Now showing items 1-5 of 5
Effects of biological compound Turkish propolis extract on breast cancer cells
(Bilkent University, 2013)
Propolis is a resinous compound which is collected from various plants then combined with wax and bee enzymes by worker bees. There are many studies conducted on propolis or its active components aiming to find new ...
Investigation of the role of cGAMP in differentiation of T lymphocytes
(Bilkent University, 2016-10)
STING is the pivotal mediator for the recognition of host and pathogenic cytosolic dsDNA as well as cyclic di-nucleotides metabolites from microbes. STING can either recognize DNA itself or sense the presence of cGAMP, ...
Functional analysis of Erbin gene in breast cancer drug resistance
(Bilkent University, 2021-02)
Erbin is an ERBB2 interacting protein with roles in many signaling pathways. Breast cancer is one of the types of cancer that is affected by Erbin regulation. However, it is unclear how Erbin regulates the biological ...
Elucidating the mechanisms of T-DM1 resistance in in vitro models of HER2 overexpressing breast cancer
(Bilkent University, 2016-09)
Despite the presence of plethora of anti-cancer therapeutics with a variety of different mechanisms of action, it is still not possible to completely eradicate cancer due largely to the occurrence of refractory tumors even ...
Characterization of programmed cell death induced by oxidative stress in selenium - deficient hepatocellular carcinoma cells
(Bilkent University, 1999)
Selenium (Se) plays an important role in eliminating the reactive oxygen species generated during oxidative stress. Se-containing selenocysteine is an essential amino acid required for the synthesis of many selenoproteins, ...