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Elucidation of Sorafenib resistance mechanisms in hepatocellular carcinoma
(Bilkent University, 2018-07)
Hepatocellular Carcinoma (HCC) is the sixth most common type of cancer and the second leading cause of cancer-related deaths worldwide. Currently, Sorafenib is the only approved first-line treatment option for unresectable ...
Immunomodulatory effects of exosomes: promising candidates in immunotherapy
(Bilkent University, 2018-08)
Exosomes are type of extracellular vesicles secreted from almost all cell types and
carry numerous biological molecules such as nucleic acids, protein and lipids. They
mediate many cellular processes including cellular ...
Identification of the roles played by IKKε in hepatocellular and colorectal carcinogenesis
(Bilkent University, 2018-07)
Hepatocellular carcinomas (HCC) and colorectal carcinomas (CRC) are among the most common cancers worldwide with high mortality rates. While HCC affecting mostly underdeveloped countries, CRC is a disease that mainly occur ...