Advisors
Now showing items 1-9 of 9
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Diverse SNP selection for epistasis test prioritization
(Bilkent University, 2019-08)Genome-wide association studies explain a fraction of the underlying heritability of genetic diseases. Epistatic interactions between two or more loci help closing the gap and identifying those complex interactions ... -
Doubletdetector: a method to detect doublet cells in open chromatin regions
(Bilkent University, 2020-09)Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a simple and effective technique in genomic studies that shows the chromatin accessibility of the genome. The open regions of the genome play an ... -
Graph embeddings on protein interaction networks
(Bilkent University, 2019-02)Protein-protein interaction (PPI) networks represent the possible set of interactions among proteins and thereby the genes that code for them. By integrating isolated signals on single genes such as mutations or differential ... -
Machine learning assisted intraoperative assessment of brain tumor margins using HRMAS NMR spectroscopy
(Bilkent University, 2021-07)Complete resection of the tumor is important for survival in glioma patients. Even if the gross total resection was achieved, left-over micro-scale tissue in the excision cavity risks recurrence. High Resolution Magic Angle ... -
PAMOGK-Web: a framework for cancer subtype identification using copy number variatıons
(Bilkent University, 2020-12)Detection of molecular sub-groups of cancer is important for developing cancer therapeutics and to understand the underlying causes of the molecular differences in these groups. The cancer sequencing projects made multi-omics ... -
Polishing copy number variant calls on exome sequencing data VIA deep learning
(Bilkent University, 2021-07)Accurate and efficient detection of copy number variants (CNVs) is of critical importance due to their significant association with complex genetic diseases. Although algorithms that use whole genome sequencing (WGS) data ... -
Predicting carbon spectrum in heteronuclear single quantum coherence spectroscopy for online feedback during surgery
(Bilkent University, 2020-09)1H High-Resolution Magic Angle Spinning (HRMAS) Nuclear Magnetic Resonance (NMR) is a reliable technology used for detecting metabolites in solid tissues. Fast response time enables guiding surgeons in real time, for ... -
Predicting informative spatio-temporal neurodevelopmental windows and gene risk for autism spectrum disorder
(Bilkent University, 2020-10)Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with a strong genetic basis. Due to its intricate nature, only a fraction of the risk genes were identified despite the effort spent on large-scale ... -
Spatio-temporal gene discovery for autism spectrum disorder
(Bilkent University, 2018-05)Whole Exome Sequencing (WES) studies for Autism Spectrum Disorder (ASD) could identify only around six dozen risk genes to date, because the genetic architecture of the disorder is highly complex. To speed the gene ...
