Now showing items 1-3 of 3
Mesenchymal stem cell mechanics on osteoinductive peptide nanofibers
(Bilkent University, 2017-08)
In this thesis, changes in Young's modulus of mesenchymal stem cells (MSCs) were investigated during their osteogenic differentiation on bioactive peptide nanofibers that bear triple glutamic acid sequence (EEE), a ...
Self-assembled peptide nanostructure delivery sytems for oligonucleotide therapy
(Bilkent University, 2014-06)
Oligonucleotides are potent therapeutic agents in the treatment of cancer, metabolic, cardiovascular and various hereditary diseases. Despite their great potential, oligonucleotide-based drugs have failed in clinical and ...
Self-assembled peptide based biomaterials for drug delivery and regenerative medicine
(Bilkent University, 2016-06)
Self-assembly is a nature inspired novel engineering tool to build functional new generation of adaptable and complex biomaterials with variety of chemical and physical properties based on recent discoveries at the ...