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Identification and characterization of two endoplasmic reticulum protein isoforms encoded by senescence-associated FAM134B gene
(Bilkent University, 2008)
Liver cancer is the fifth most common cancer in the world. Until recently, tumor cells were known to have the capacity to proliferate indefinitely. In a previous study, we showed the spontaneous induction of replicative ...
Lipotoxic endoplasmic reticulum stress-associated inflammation : molecular mechanisms and modification by a bioactive lipokine
(Bilkent University, 2012)
Physiologic or pathologic processes that disturb protein folding in the endoplasmic reticulum (ER) activate a signaling pathway named the unfolded protein response (UPR). UPR promotes cell survival by reducing misfolded ...
Characterization of FAM134B in the context of hepatocellular carcinoma and endoplasmic reticulum protein stress
(Bilkent University, 2011)
Family with sequence similarity 134, member B (FAM134B) is a replicative senescence associated gene, previously identified in studies of our group as a result of microarray analysis in spontaneously senescent clones of ...