Now showing items 1-2 of 2
Immunotherapeutic applications of nucleic acid based tlr agonists and antagonists
(Bilkent University, 2014)
Recent evidence suggests that genetic material is not just the blueprint of life. Depending on the type of the source that genomic material is extracted or the type of motif that DNA harbors DNA could be immunostimulatory ...
Suppressive oligodeoxynucleotides as a TLR antagonist : efforts to treat autoimmune diseases
(Bilkent University, 2007)
Synthetic oligodeoxynucleotides (ODN) expressing suppressive TTAGGG motifs effectively down-regulate the production of proinflammatory and Th1 cytokines elicited by a variety of Toll-Like Receptor (TLR) dependent or ...