Now showing items 1-6 of 6
Gene Expression changes in aging zebrafish (Danio rerio) brains are sexually dimorphic
(BioMed Central, 2014)
Background: Brain aging is a multi-factorial process due to both genetic and environmental factors. The zebrafish has recently become a popular model organism for examining aging and age-related diseases because as ...
Systematic discovery of Rab GTPases with synaptic functions in Drosophila
Background: Neurons require highly specialized intracellular membrane trafficking, especially at synapses. Rab GTPases are considered master regulators of membrane trafficking in all cells, and only very few Rabs have known ...
Oscillatory synchronization model of attention to moving objects
The world is a dynamic environment hence it is important for the visual system to be able to deploy attention on moving objects and attentively track them. Psychophysical experiments indicate that processes of both attentional ...
Homozygosity mapping and targeted genomic sequencing reveal the game responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred
(Cold Spring Harbor Laboratory Press, 2011-09-01)
The biological basis for the development of the cerebro-cerebellar structures required for posture and gait in humans is poorly understood. We investigated a large consanguineous family from Turkey exhibiting an extremely ...
Aging alters the molecular dynamics of synapses in a sexually dimorphic pattern in zebrafish (Danio rerio)
The zebrafish has become a popular model for studying normal brain aging due to its large fecundity, conserved genome, and available genetic tools; but little data exists about neurobiological age-related alterations. The ...
Short-term dietary restriction in old zebrafish changes cell senescence mechanisms
Brain aging is marked by a decline in cognitive abilities and associated with neurodegenerative disorders. Recent studies have shown, neurogenesis continues into adulthood but is known to be decreasing during advancing age ...