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Schizophrenia polygenic risk score influence on white matter microstructure

Simões, B.; Vassos, E.; Shergill, S.; McDonald, C.; Toulopoulou, Timothea; Kalidindi, S.; Kane, F.; Murray, R.; Bramon, E.; Ferreira, H.; Prata, D. (Elsevier, 2020)

Schizophrenia (SZ) and bipolar disorder (BD) are highly heritable, share symptomatology, and have a polygenic architecture. The impact of recent polygenic risk scores (PRS) for psychosis, which combine multiple genome-wide ...

Intelligence, educational attainment, and brain structure in those at familial high‐risk for schizophrenia or bipolar disorder

de Zwarte, S. M. C.; Brouwer, R.; Agartz, I.; Alda, M.; Alonso-Lana, S.; Bearden, C.; Bertolino, A.; Bonvino, A.; Bramon, E.; Buimer, E.; Cahn, W.; Canales-Rodríguez, E.; Cannon, D. M.; Cannon, T. D.; Caseras, X.; Castro-Fornieles, J.; Chen, Q.; Chung, Y.; De la Serna, E.; del Mar Bonnin, C.; Demro, C.; Di Giorgio, A.; Doucet, G.; Eker, M.; Erk, S.; Fatjó-Vilas, M.; Fears, S.; Foley, S.; Frangou, S.; Fullerton, J.; Glahn, D.; Goghari, V.; Goikolea, J.; Goldman, A.; Gonul, A.; Gruber, O.; Hajek, T.; Hawkins, E.; Heinz, A.; Ongun, C.; Hillegers, M.; Houenou, J.; Pol, H.; Hultman, C.; Ingvar, M.; Johansson, V.; Jönsson, E.; Kane, F.; Kempton, M.; Koenis, M.; Kopecek, M.; Krämer, B.; Lawrie, S.; Lenroot, R.; Marcelis, M.; Mattay, V.; McDonald, C.; Meyer-Lindenberg, A.; Michielse, S.; Mitchell, P.; Moreno, D.; Murray, R.; Mwangi, B.; Nabulsi, L.; Newport, J.; Olman, C.; van Os, J.; Overs, B.; Ozerdem, A.; Pergola, G.; Picchioni, M.; Piguet, C.; Pomarol-Clotet, E.; Radua, J.; Ramsay, I.; Richter, A.; Roberts, G.; Salvador, R.; Saricicek-Aydogan, A.; Sarró, S.; Schofield, P.; Simsek, E.; Simsek, F.; Soares, J.; Sponheim, S.; Sugranyes, G.; Toulopoulou, Timothea; Tronchin, G.; Vieta, E.; Walter, H.; Weinberger, D.; Whalley, H.; Wu, M. -J.; Yalin, N.; Andreassen, O.; Ching, C.; Thomopoulos, S.; van Erp, T.; Jahanshad, N.; Thompson, P.; Kahn, R.; van Haren, N. (Wiley, 2020)

First‐degree relatives of patients diagnosed with schizophrenia (SZ‐FDRs) show similar patterns of brain abnormalities and cognitive alterations to patients, albeit with smaller effect sizes. First‐degree relatives of ...

Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study

Thygesen, J. H.; Presman, A.; Harju-Seppanen, J.; Irizar, H.; Jones, R.; Kuchenbaecker, K.; Lin, K.; Alizadeh, B. Z.; Austin-Zimmerman, I.; Bartels-Velthuis, A.; Bhat, A.; Bruggeman, R.; Cahn, W.; Calafato, S.; Crespo-Facorro, B.; De Haan, L.; De Zwarte, S. M. C.; Di Forti, M.; Diez-Revuelta, A.; Hall, J.; Hall, M.-H.; Iyegbe, C.; Jablensky, A.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lawrie, S.; Luykx, J. J.; Mata, I.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Muir, R.; Ophoff, R.; Picchioni, M.; Prata, D. P.; Ranlund, S.; Rujescu, D.; Rutten, B. P. F.; Schulze, K.; Shaikh, M.; Schirmbeck, F.; Simons, C. J. P.; Toulopoulou, Timothea; Van Amelsvoort, T.; Van Haren, N.; Van Os, J.; Van Winkel, R.; Vassos, E.; Walshe, M.; Weisbrod, M.; Zartaloudi, E.; Bell, V.; Powell, J.; Lewis, C. M.; Murray, R. M.; Bramon, E. (Springer Nature, 2020)

The burden of large and rare copy number genetic variants (CNVs) as well as certain specific CNVs increase the risk of developing schizophrenia. Several cognitive measures are purported schizophrenia endophenotypes and may ...

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Schizophrenia polygenic risk score influence on white matter microstructure

Intelligence, educational attainment, and brain structure in those at familial high‐risk for schizophrenia or bipolar disorder

Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study