Browsing by Keywords "c-Src"

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    • Predictive gene signature for pyrazolopyrimidine derivative c-Src inhibitor 10a sensitivity in melanoma cells 

      Kücükkaraduman, Barış; Türk, C.; Fallacara, A. L.; Şenses, K. M.; Ayyıldız, Z. O.; Akbar, Muhammad W.; Lotem, Michal; Botta, M.; İşbilen, M.; Güre, Ali O. (American Chemical Society, 2020-02)
      Melanoma is a highly aggressive cancer with poor prognosis. Although more than 80% of melanomas harbor an activating mutation in genes within the MAPK pathway, which are mutually exclusive, usefulness of therapies targeting ...