Browsing by Keywords "bone marrow cell"

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The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity

Sag, D.; Cekic, C.; Wu, R.; Linden J.; Hedrick, C.C. (Nature Publishing Group, 2015)

ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol efflux from cells and regulates intracellular cholesterol homeostasis. Here we demonstrate a role of ABCG1 as a mediator of tumour immunity. Abcg1-/- mice ...
Effect of double growth factor release on cartilage tissue engineering

Ertan, A.B.; Yilgor P.; Bayyurt, B.; Çalikoǧlu, A.C.; Kaspar Ç.; Kök F.N.; Kose G.T.; Hasirci V. (2013)

The effects of double release of insulin-like growth factor I (IGF-I) and growth factor β1 (TGF-β1) from nanoparticles on the growth of bone marrow mesenchymal stem cells and their differentiation into cartilage cells were ...
Myeloid expression of adenosine a2A receptor suppresses T and NK cell responses in the solid tumor microenvironment

Cekic, C.; Day, Y.-J.; Sag, D.; Linden J. (American Association for Cancer Research Inc., 2014)

High concentrations of adenosine in tumor microenvironments inhibit antitumor cytotoxic lymphocyte responses. Although T cells express inhibitory adenosine A2A receptors (A2AR) that suppress their activation and inhibit ...