Now showing items 1-2 of 2

    • Polygenic risk score increases schizophrenia liability through cognition-relevant pathways 

      Toulopoulou, Timothea; Zhang, X.; Cherny, S.; Dickinson, D.; Berman, K. F.; Straub, R. E.; Sham, P.; Weinberger, D. R. (Oxford University Press, 2019-02)
      Cognitive deficit is thought to represent, at least in part, genetic mechanisms of risk for schizophrenia, with recent evidence from statistical modelling of twin data suggesting direct causality from the former to the ...
    • Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders 

      Calafato, M. S.; Thygesen, J. H.; Ranlund, S.; Zartaloudi, E.; Cahn, W.; Crespo-Facorro, B.; Díez-Revuelta, A.; Forti, M. D.; Hall, M. -H.; Iyegbe, C.; Jablensky, A.; Kahn, R.; Kalaydjieva, L.; Kravariti, E.; Lin, K.; McDonald, C.; McIntosh, A. M.; McQuillin, A.; Picchioni, M.; Rujescu, D.; Shaikh, M.; Toulopoulou, T.; Os, J. V.; Vassos, E.; Walshe, M.; Powell, J.; Lewis, C. M.; Murray, R. M.; Bramon, E. (2018)
      Background There is increasing evidence for shared genetic susceptibility between schizophrenia and bipolar disorder. Although genetic variants only convey subtle increases in risk individually, their combination into a ...