Browsing by Keywords "Photosensitizer"
Now showing items 1-9 of 9
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Chemical modulation of singlet oxygen generation rates in thermal endoperoxide decomposition & novel fluorescent sensors for hyperphosporylated tau proteins
(Bilkent University, 2016-05)Chemical control over singlet oxygen generation is an open to improvement because of the importance of this reactive species in biological systems. In the first project, we aimed to synthesize a silylated 1,4-dimethylnaphthalene ... -
Covalently functionalized MSNs as potential photosensitizing agents for PDT
(Bilkent University, 2011)Photodynamic therapy (PDT) is a novel approach for the treatment of some cancers and other non-malignant diseases. PDT aims to kill cancer tissue by the generation of singlet oxygen as a result of excitation of the ... -
Cucurbit[7]uril-anchored porphyrin-based multifunctional molecular platform for photodynamic antimicrobial and cancer therapy
(American Chemical Society, 2019)Here we report a photoactive supramolecular assembly that is multifunctional and constructed by covalently linking four receptor molecules (cucurbit[7]uril) to a porphyrin derivative with suitable linkers. While this ... -
Energy transfer, photosensitization and sensing with novel bodipy compounds and their supramolecular assemblies
(Bilkent University, 2017-06)Fluorescent dyes have been used for decades in many applications due to their versatility, sensitivity and many other useful properties. Since their discovery in 1968, BODIPY dyes have come forward and have been used in ... -
An exploration of new avenues regarding deep tissue penetration and higher singlet oxygen efficiencies: novel near-IR photosensitizers for photodynamic therapy
(TÜBİTAK, 2019)A series of novel BODIPY-bearing electron-withdrawing groups at the meso position are reported here. According to the optical measurements, it may be clearly seen that the introduction of electron-donating groups into ... -
Metal ion release and signaling in molecular logic gate design
(Bilkent University, 2016-10)Mimicking the biological structures is one of the main goals of the natural sciences, because processes are well-organized in nature despite its amazing complexity. On account of this, releasing metal ions at molecular ... -
Near IR absorbing bodipy-functionalized SPIONs: a potential magnetic nanoplatform for diagnosis and therapy
(De Gruyter, 2014)Photodynamic therapy (PDT), especially with the recent advances in photosensitizer (PS) design, has already been established as a noninvasive technique for cancer treatment. Recently, near-IR-based absorbing PSs that have ... -
Photodynamic therapy—current limitations and novel approaches
(Frontiers Research Foundation, 2021-06-10)Photodynamic therapy (PDT) mostly relies on the generation of singlet oxygen, via the excitation of a photosensitizer, so that target tumor cells can be destroyed. PDT can be applied in the settings of several malignant ... -
Towards therapeutic automata and hypoxia activated singlet oxygen generators
(Bilkent University, 2019-08)Photodynamic therapy (PDT) is a treatment modality depends on the efficient generation of singlet oxygen (1O2) through excitation of a particular chromophore (sensitizer) followed by an energy transfer to the dissolved ...
