Browsing by Keywords "Osteogenic differentiation"
Now showing items 1-7 of 7
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Alkaline phosphatase-mimicking peptide nanofibers for osteogenic differentiation
(American Chemical Society, 2015)Recognition of molecules and regulation of extracellular matrix synthesis are some of the functions of enzymes in addition to their catalytic activity. While a diverse array of enzyme-like materials have been developed, ... -
Development of peptide based materials as a synthetic scaffold to mimic extracellular matrix
(Bilkent University, 2017-07)Biomaterials obtained through self-assembling process of peptide amphiphile (PA) molecules provide great potential to introduce new therapeutic approaches in regenerative medicine through mimicking the natural environments ... -
A glycosaminoglycan mimetic peptide nanofiber gel as an osteoinductive scaffold
(Royal Society of Chemistry, 2016)Biomineralization of the extracellular matrix (ECM) plays a crucial role in bone formation. Functional and structural biomimetic native bone ECM components can therefore be used to change the fate of stem cells and induce ... -
Glycosaminoglycan-Mimetic Signals Direct the Osteo/Chondrogenic Differentiation of Mesenchymal Stem Cells in a Three-Dimensional Peptide Nanofiber Extracellular Matrix Mimetic Environment
(American Chemical Society, 2016-02)Recent efforts in bioactive scaffold development focus strongly on the elucidation of complex cellular responses through the use of synthetic systems. Designing synthetic extracellular matrix (ECM) materials must be based ... -
Mineralized peptide nanofiber gels for enhanced osteogenic differentiation
(Wiley, 2018)Mineral deposition is observed in both bacterial and eukaryotic organisms through a broad range of mechanisms. Both organic and inorganic components play crucial roles in the formation of mineralized tissues, and acidic ... -
Nanomechanical characterization of osteogenic differentiation of mesenchymal stem cells on bioactive peptide nanofiber hydrogels
(Wiley-VCH Verlag, 2017-08)Stem cell differentiation is known to be influenced by the mechanical properties of the surrounding extracellular matrix (ECM); however, little is known about the mechanical phenotypes of differentiating stem cells within ... -
Synthesis and characterization of nanosized calcium phosphates by flame spray pyrolysis, and their effect on osteogenic differentiation of stem cells
(Springer, 2015)The present study evaluates the synthesis of biocompatible osteoconductive and osteoinductive nano calcium phosphate (CaP) particles by industrially applied, aerosol-derived flame spray pyrolysis method for biomedical ...