Now showing items 1-4 of 4

    • Functionally conserved effects of rapamycin exposure on zebrafish 

      Sucularli, C.; Shehwana, H.; Kuscu, C.; Dungul, D. C.; Ozdag, H.; Konu, O. (Spandidos Publications, 2016-03)
      Mechanistic target of rapamycin (mTOR) is a conserved serine/threonine kinase important in cell proliferation, growth and protein translation. Rapamycin, a well-known anti-cancer agent and immunosuppressant drug, inhibits ...
    • Interplay between 15-lipoxygenase-1 and metastasisassociated antigen 1 in the metastatic potential of colorectal cancer 

      Tunçer, S.; Çağatay, T. S.; Keşküş, A. G.; Çolakoğlu, M.; Konu, Ö.; Banerjee S. (Wiley-Blackwell Publishing Ltd., 2016)
      Objectives: Metastasis-associated antigen 1 (MTA1) is implicated in metastasis while 15-lipoxygenase-1 (15-LOX-1) reduces cell motility, when re-expressed in colorectal cancer (CRC). We aimed to understand any potential ...
    • MicroRNA expression patterns in canine mammary cancer show significant differences between metastatic and non-metastatic tumours 

      Bulkowska, M.; Rybicka, A.; Senses, K. M.; Ulewicz, K.; Witt, K.; Szymanska, J.; Taciak, B.; Klopfleisch, R.; Hellmén, E.; Dolka, I.; Gure, A. O.; Mucha, J.; Mikow, M.; Gizinski, S.; Krol, M. (BioMed Central Ltd., 2017)
      Background: MicroRNAs may act as oncogenes or tumour suppressor genes, which make these small molecules potential diagnostic/prognostic factors and targets for anticancer therapies. Several common oncogenic microRNAs have ...
    • PATIKAmad: putting microarray data into pathway context 

      Babur, O.; Colak, R.; Demir, E.; Dogrusoz, U. (Wiley - V C H Verlag GmbH & Co. KGaA, 2008-06)
      High-throughput experiments, most significantly DNA microarrays, provide us with system-scale profiles. Connecting these data with existing biological networks poses a formidable challenge to uncover facts about a cell's ...