Browsing by Keywords "Mammalian target of rapamycin complex 1"
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TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT (Nature Publishing Group, 2017)Intrinsic and acquired resistance to chemotherapy is the fundamental reason for treatment failure for many cancer patients. The identification of molecular mechanisms involved in drug resistance or sensitization is imperative. ...