Browsing by Keywords "Liposome"
Now showing items 1-5 of 5
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Cell penetrating peptide amphiphile integrated liposomal systems for enhanced delivery of cargo to tumor cells
(Bilkent University, 2013)Liposomes have been extensively utilized as effective nanocarriers due to their enhanced solubility, higher stability and greater ability to facilitate the slow release of encapsulated drugs compared to free drug ... -
FTIR studies of vitamin E-cholesterol-DPPC membrane interactions in CH2 region
(Springer-Verlag, 1996)Binary and ternary mixtures of α-tocopherol (αT), cholesterol and dipalmitoyl phosphatidylcholine (DPPC) in the form of multilamellar liposomes have been investigated by Fourier Transform Infrared Spectroscopy (FTIR). ... -
Inflammasome induction and immunostimulatory effects of CpG-ODN loaded liposomes containing DC-cholesterol
(Turkish Society of Immunology, 2013)Objectives: This study aims to investigate the effects of cholesterol content and cationic property of liposomes on immune response. Materials and methods: Liposomes containing high amounts of 3β-[N-(N',N'-dimethylaminoe ... -
Investigation of improved immunostimulatory activity of D and K type CpG ODNs in liposomes
(Bilkent University, 2013)CpG ODNs are potent immunotherapeutic agents. In human, two major classes of CpG ODNs were shown to induce differential immune activation. D ODNs are strong IFNα inducers, thus promising antiviral agents, whereas K ODNs ... -
Site-specific fluorescence polarization for studying the disaggregation of α-synuclein fibrils by small molecules
(American Chemical Society, 2017)Fibrillar aggregates of the protein α-synuclein (αS) are one of the hallmarks of Parkinson’s disease. Here, we show that measuring the fluorescence polarization (FP) of labels at several sites on αS allows one to monitor ...