Browsing by Keywords "Benzothiazole"

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Evaluation of inhibitory effects of benzothiazole and 3-amino-benzothiazolium derivatives on DNA topoisomerase II by molecular modeling studies

Akı-Yalçın, E.; Ertan-Bolelli, T.; Taşkın-Tok, T.; Öztürk, Ö.; Ataei, S.; Özen, Çiğdem; Yıldız, I.; Yalçın, I. (Taylor and Francis, 2014)

There has been considerable interest in DNA topoisomerases over the last decade, as they have been shown to be one of the major cellular targets in anticancer drug development. Previously we synthesized some benzothiazole ...
Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives

Gurdal, E.E.; Buclulgan, E.; Durmaz I.; Cetin-Atalay, R.; Yarim, M. (Bentham Science Publishers B.V., 2015)

Synthesis, characterization and cytotoxic activities of ten benzothiazole-piperazine derivatives were reported. In vitro cytotoxic activities of compounds were screened against hepatocellular (HUH-7), breast (MCF-7) and ...