Now showing items 1-6 of 6

    • Bioactive self-assembled peptide nanofibers for corneal stroma regeneration 

      Uzunalli, G.; Soran, Z.; Erkal, T. S.; Dagdas, Y. S.; Dinc, E.; Hondur, A. M.; Bilgihan, K.; Aydin B.; Guler, M. O.; Tekinay, A. B. (Elsevier, 2014)
      Defects in the corneal stroma caused by trauma or diseases such as macular corneal dystrophy and keratoconus can be detrimental for vision. Development of therapeutic methods to enhance corneal regeneration is essential ...
    • Implicit motif distribution based hybrid computational kernel for sequence classification 

      Atalay, V.; Cetin Atalay, R. (Oxford University Press, 2005)
      Motivation: We designed a general computational kernel for classification problems that require specific motif extraction and search from sequences. Instead of searching for explicit motifs, our approach finds the distribution ...
    • Lack of association between RNASEL Arg462Gln variant and the risk of breast cancer 

      Sevinç, A.; Yannoukakos, D.; Konstantopoulou, I.; Manguoglu, E.; Lüleci, G.; Çolak, T.; Akyerli, C.; Çolakoglu, G.; Tez, M.; Sayek, I.; Gerassimos, V.; Nasioulas, G.; Papadopoulou, E.; Florentin, L.; Kontogianni, E.; Bozkurt, B.; Kocabas, N. A.; Karakaya, A. E.; Yulug, I. G.; Özçelik, T. (International Institute of Anticancer Research, 2004)
      Background: The RNASEL G1385A variant was recently found to be implicated in the development of prostate cancer. Considering the function of RNase L and the pleiotropic effects of mutations associated with cancer, we sought ...
    • Multivalent presentation of cationic peptides on supramolecular nanofibers for antimicrobial activity 

      Beter, M.; Kara, H. K.; Topal, A. E.; Dana, A.; Tekinay, A. B.; Guler, M. O. (American Chemical Society, 2017)
      Noncovalent and electrostatic interactions facilitate the formation of complex networks through molecular self-assembly in biomolecules such as proteins and glycosaminoglycans. Self-assembling peptide amphiphiles (PA) are ...
    • Self-assembled peptide amphiphile nanofibers and PEG composite hydrogels as tunable ECM mimetic microenvironment 

      Goktas, M.; Cinar, G.; Orujalipoor, I.; Ide, S.; Tekinay, A. B.; Guler, M. O. (American Chemical Society, 2015)
      (Figure Presented). Natural extracellular matrix (ECM) consists of complex signals interacting with each other to organize cellular behavior and responses. This sophisticated microenvironment can be mimicked by advanced ...
    • Supramolecular chirality in self-assembled peptide amphiphile nanostructures 

      Garifullin, R.; Guler, M. O. (Royal Society of Chemistry, 2015)
      Induced supramolecular chirality was investigated in the self-assembled peptide amphiphile (PA) nanosystems. Having shown that peptide chirality can be transferred to the covalently-attached achiral pyrene moiety upon PA ...