Now showing items 1-5 of 5

    • Colon cancer associated transcript-1 (CCAT1) expression in adenocarcinoma of the stomach 

      Mizrahi, I.; Mazeh, H.; Grinbaum, R.; Beglaibter, N.; Wilschanski, M.; Pavlov, V.; Adileh, M.; Stojadinovic, A.; Avital, I.; Gure, A. O.; Halle, D.; Nissan, A. (Ivyspring International Publisher, 2015)
      Background: Long non-coding RNAs (lncRNAs) have been shown to have functional roles in cancer biology and are dys-regulated in many tumors. Colon Cancer Associated Transcript -1 (CCAT1) is a lncRNA, previously shown to be ...
    • Colon cancer associated transcript-1: a novel RNA expressed in malignant and pre-malignant human tissues 

      Nissan, A.; Stojadinovic, A.; Rosenbaum, S. M.; Halle, D.; Grinbaum, R.; Roistacher, M.; Bochem, A.; Dayanc, B. E.; Ritter, G.; Gomceli, I.; Bostanci, E. B.; Akoglu, M.; Chen, Y. T.; Old, L. J.; Gure, A. O. (Wiley, 2012)
      Early detection of colorectal cancer (CRC) is currently based on fecal occult blood testing (FOBT) and colonoscopy, both which can significantly reduce CRC-related mortality. However, FOBT has low-sensitivity and specificity, ...
    • Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT–PNA molecular beacons 

      Kam, Y.; Rubinstein, A.; Naik, S.; Djavsarov, I.; Halle, D.; Ariel, I.; Gure, A. O.; Stojadinovic, A.; Pan, H. G.; Tsivin, V.; Nissan, A.; Yavin, E. (Elsevier Ireland Ltd., 2014-09-28)
      Although the function and mechanism of action of long non-coding RNAs (lncRNA) is still not completely known, studies have shown their potential role in the control of gene expression and regulation, in cellular proliferation ...
    • Differential expression of colon cancer associated transcript1 (CCAT1) along the colonic adenoma-carcinoma sequence 

      Alaiyan, B.; Ilyayev, N.; Stojadinovic, A.; Izadjoo, M.; Roistacher, M.; Pavlov, V.; Tzivin, V.; Halle, D.; Pan, H.; Trink, B.; Gure, A. O.; Nissan, A. (BioMed Central, 2013)
      Background: The transition from normal epithelium to adenoma and, to invasive carcinoma in the human colon is associated with acquired molecular events taking 5-10 years for malignant transformation. We discovered CCAT1, ...
    • Early detection and staging of colorectal cancer using a panel of micro RNAs 

      Shapira, R.; Ilyayev, N.; Attali, R.; Westrich, G.; Halle, D.; Speter, C.; Stavropoulos, A. V.; Roistacher, M.; Pavlov, V.; Grinbaum, R.; Protic, P.; Güre, Ali O.; Bilchik, A. J.; Stojadinovic, A.; Mitrani-Rosenbaum, S.; Nissan, A. (OMICS, 2018)
      Purpose: To improve lymph node (LN) staging in patients with colon cancer (CC). The present study describes the selection of CC-specific miRNAs and assesses their utility as a micro metastases detection assay. Methods: ...