Now showing items 1-2 of 2

    • PDE control of a rotating shear beam with boundary feedback 

      Doğan, M.; Morgül, Ömer (IEEE, 2009-08)
      We consider a flexible structure modeled as a shear beam which is clamped to a rigid body at one end and is free at the other end. The whole structure is free to rotate on the horizontal plane. We first model the system ...
    • Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer 

      Saatçi, Ö.; Kaymak, A.; Raza, Umar; Ersan, Pelin G.; Akbulut, Özge; Banister, C. E.; Sikirzhytski, V.; Tokat, Ünal Metin; Aykut, Gamze; Ansari, Suhail A.; Tatlı-Doğan, H.; Doğan, M.; Jandaghi, P.; Işık, A.; Gündoğdu, F.; Kösemehmetoğlu, K.; Dizdar, Ö.; Aksoy, S.; Akyol, A.; Üner, A.; Buckhaults, P. J.; Riazalhosseini, Y.; Şahin, Özgür (Nature Research, 2020)
      Chemoresistance is a major obstacle in triple negative breast cancer (TNBC), the most aggressive breast cancer subtype. Here we identify hypoxia-induced ECM re-modeler, lysyl oxidase (LOX) as a key inducer of chemoresistance ...