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Analysis of the function of the nuclear matrix-associated protein C1D
(Bilkent University, 1999)DNA Double-strand breaks (DSBs) are generated as intermediate stnictures during V(D)J recombination, as a consequence of oxidative metabolism, or can be induced by exogenous factors such as gamma irradiation and radiomimetic ... -
Identification of the role of the nuclear matrix protein C1D in DNA repair and recombination
(Bilkent University, 2002)The nuclear matrix protein C1D is an activator of the DNA dependent protein kinase (DNA-PK), which is essential for the repair of DNA double-strand breaks (DNA-DSBs). C1D is phosphorylated very efficiently by DNA-PK, and ... -
Role of the nuclear matrix protein C1D in regulation of transcription
(Bilkent University, 2001)The nuclear matrix protein C1D is an activator of DNA-dependent protein kinase (DNAPK), which is involved in non-homologous end joining and V(D)J recombination. Moreover, the nuclear matrix proteins C1D was shown to be ...
